Chloroprocaine (hydrochloride)

Chloroprocaine hydrochloride (2-Chloroprocaine hydrochloride) is a potent inhibitor of Na, K-ATPase activity with an IC50 of 13 mM. Chloroprocaine hydrochloride blocks peripheral nerve[1].

Product Specifications

CAS Number

[3858-89-7]

Product Name Alternative

2-Chloroprocaine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Na+/K+ ATPase

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/chloroprocaine-hydrochloride.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : 83.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(OCCN(CC)CC)C1=CC=C(N)C=C1Cl.[H]Cl

Molecular Formula

C13H20Cl2N2O2

Molecular Weight

307.22

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]H Kutchai, et al. Inhibition of the Na, K-ATPase of Canine Renal Medulla by Several Local Anesthetics. Pharmacol Res. 2001 Apr;43 (4) :399-403.|[2]Chloroprocaine HCl Injection.