Acetyl podocarpic acid anhydride

Acetyl podocarpic acid anhydride is a potent, semisynthetic liver X receptor (LXR) agonist derived from extracts of the mayapple. Acetyl podocarpic acid anhydride has the potential to be useful for the prevention and research of atherosclerosis, especially in the context of low HDL levels[1].

Product Specifications

CAS Number

[344327-48-6]

Product Name Alternative

Acetylpodocarpic dimer; APD

UNSPSC

12352005

Target

LXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/acetyl-podocarpic-acid-anhydride.html

Purity

99.0

Solubility

DMF : 1 mg/mL (ultrasonic; warming)

Smiles

O=C(OC([C@@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=CC(OC(C)=O)=C3)=O)[C@@]4(C)CCC[C@]5(C)C6=C(CC[C@@]45[H])C=CC(OC(C)=O)=C6

Molecular Formula

C38H46O7

Molecular Weight

614.77

References & Citations

[1]Sparrow CP, et al. A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux. J Biol Chem. 2002 Mar 22;277 (12) :10021-7.