ML303

ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1[1].

Product Specifications

CAS Number

[1638211-04-7]

UNSPSC

12352005

Hazard Statement

H301

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ml303.html

Purity

99.62

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2=CC=NC3=C2C(C)=NN3C4=CC=C(C(F)(F)F)C=C4)C=C1OC

Molecular Formula

C21H16F3N3O2

Molecular Weight

399.37

Precautions

P264-P270-P330-P405-P501

References & Citations

[1]Patnaik S, et al. Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists. Bioorg Med Chem Lett. 2019 May 1;29 (9) :1113-1119.