N-Decanoyl-L-homoserine lactone

N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots[1].

Product Specifications

CAS Number

[177315-87-6]

Product Name Alternative

C10-HSL

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Bacterial; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/n-decanoyl-l-homoserine-lactone.html

Purity

98.40

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCC(N[C@@H]1C(OCC1)=O)=O

Molecular Formula

C14H25NO3

Molecular Weight

255.35

Precautions

H315, H319, H335

References & Citations

[1]Cao XY, et al. Cellular messengers involved in the inhibition of the Arabidopsis primary root growth by bacterial quorum-sensing signal N-decanoyl-L-homoserine lactone. BMC Plant Biol. 2022 Oct 14;22 (1) :488.|[2]Xin Lu, et al. Bacterial signal C10-HSL stimulates spore germination of Galactomyces geotrichum by transboundary interaction. Chinese Chemical Letters. 2022.