Kumujian A

Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL) [1].

Product Specifications

CAS Number

[72755-19-2]

Product Name Alternative

1-Ethoxycarbonyl-β-carboline

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/kumujian-a.html

Purity

99.48

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)OCC

Molecular Formula

C14H12N2O2

Molecular Weight

240.26

Precautions

H315, H319

References & Citations

[1]Fang HW, et al. Total synthesis of cordatanine, structural reassignment of drymaritin, and anti-inflammatory activity of synthetic precursors. Bioorg Med Chem Lett. 2015 Sep 15;25 (18) :3822-4.