Kumujian A
Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL) [1].
Product Specifications
CAS Number
[72755-19-2]
Product Name Alternative
1-Ethoxycarbonyl-β-carboline
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kumujian-a.html
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)OCC
Molecular Formula
C14H12N2O2
Molecular Weight
240.26
Precautions
H315, H319
References & Citations
[1]Fang HW, et al. Total synthesis of cordatanine, structural reassignment of drymaritin, and anti-inflammatory activity of synthetic precursors. Bioorg Med Chem Lett. 2015 Sep 15;25 (18) :3822-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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