IND81
IND81 is an orally active antiprion with IC50 value of 1.95 μM. IND81 reduces abnormal, misfolded, disease-causing forms of benign prion proteins that are normally present on or within cells[1].
Product Specifications
CAS Number
1426047-52-0
UNSPSC
12352005
Target
Prion Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ind81.html
Smiles
CC1=CC(NC2=NC(C3=CC=C(C4=CC=CC=N4)S3)=CS2)=NC=C1
Molecular Formula
C18H14N4S2
Molecular Weight
350.46
References & Citations
[1]Silber BM, et al. Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharm Res. 2013 Apr;30 (4) :932-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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