S-Methylisothiourea (sulfate)

S-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS) . S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock[1].

Product Specifications

CAS Number

[867-44-7]

UNSPSC

12352211

Hazard Statement

H302

Target

HSV; NO Synthase

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/s-methylisothiourea-sulfate.html

Purity

99.94

Solubility

DMSO : < 1 mg/mL|H2O : 65 mg/mL (ultrasonic)

Smiles

NC(SC)=N.O=S(O)(O)=O.[1/2]

Molecular Formula

C2H6N2S.1/2H2O4S

Molecular Weight

139.18

Precautions

H302

References & Citations

[1]C Szabó, et al. Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc Natl Acad Sci U S A. 1994 Dec 20; 91 (26) : 12472-12476.