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SR-144528

SR-144528 is a cannabinoid (CB) receptor 2 inverse agonist (Ki values ranging from 0.3 to 5.6 nM). Displays >700-fold selectivity for CB2 over CB1 receptors. Blocks the effects of CP-55,940 on forskolin-sensitive adenylyl cyclase activity and MAPK in CHO cells expressing CB2 receptors. Also blocks CP 55,940-induced B-cell activation.

Product Specifications

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

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