(S, R, S) -AHPC-acetyl-Pip-O-azetidine-boc
Selected Variant
HY-161207
Size: 1 Each
(S, R, S) -AHPC-acetyl-Pip-O-azetidine-boc is a conjugate of E3 ligase ligand and linker, consisting of (S, R, S) -AHPC and the corresponding Linker. (S, R, S) -AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S, R, S) -AHPC-acetyl-Pip-O-azetidine-boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-75.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(CN2CCC(CC2)OC3CN(C3)C(OC(C)(C)C)=O)=O)=O)NCC(C=C4)=CC=C4C(SC=N5)=C5C
Molecular Formula
C37H54N6O7S
Molecular Weight
726.93
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
Frequently Asked Questions
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