Cefuroxime
Cefuroxime is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime has a broad spectrum activity against Gram-positive and Gram-negative bacteria[1].
Product Specifications
CAS Number
[55268-75-2]
Product Name Alternative
Kefurox
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/cefuroxime.html
Purity
99.08
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O
Molecular Formula
C16H16N4O8S
Molecular Weight
424.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Callaghan, et al. Cefuroxime, a New Cephalosporin Antibiotic: Activity in Vitro. Antimicrob Agents Chemother. 1976 Mar;9 (3) :511-9.|[2]D M Ryan, et al. Cefuroxime, a New Cephalosporin Antibiotic: Activity in Vivo. Antimicrob Agents Chemother. 1976 Mar;9 (3) :520-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
Adv Funct Mater. 2024 Jun 19.|Diagn Microbiol Infect Dis. 2025 Nov 4;114 (2) :117181.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Nat Commun. 2023 Mar 22;14 (1) :1594.|University of Texas. 2025.|Biomed Res Int. 2018 Jul 2:2018:3579832.|Int J Antimicrob Agents. 2024 May 30:107229.|J Chem Inf Model. 2021 Apr 26;61 (4) :2016-2025.
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