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Apoptosis inducer 22

Product Specifications

UNSPSC Description

Apoptosis inducer 22 (QR-5) is an apoptosis inducer with IC50 values ​​of 63.1 and 46.5 μM for colon cancer cell lines SW480 and HT29, respectively. Apoptosis inducer 22 induces apoptosis by inhibiting the Wnt/β-catenin axis in colon cancer cells. Apoptosis inducer 22 can be used in anti-colon cancer research.

Target Antigen

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/apoptosis-inducer-22.html

Smiles

FC(F)(F)C1(CC1)C2=CC(NC(NC3=CC=CC(OC)=C3)=O)=NO2

Molecular Weight

341.29

References & Citations

[1]Suresh, et al. "Isoxazolyl-urea derivative evokes apoptosis and paraptosis by abrogating the Wnt/β-catenin axis in colon cancer cells." Chemico-Biological Interactions 399 (2024): 111143.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-161900/Apoptosis-inducer-22-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-161900/

Clinical Information

No Development Reported

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