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Phenylglyoxylic acid-d5

Phenylglyoxylic acid-d5 (Benzoylformic acid-d5) is a deuterium labeled Phenylglyoxylic acid. Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds[1][2].

Product Specifications

CAS Number

1217089-53-6

Product Name Alternative

Benzoylformic acid-d5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate; Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

OC(C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)=O

Molecular Formula

C8HD5O3

Molecular Weight

155.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Capella KM, et al. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012. Environ Res. 2019 Apr;171:101-110.|[2]Leont'eva L I, et al. Antiinflammatory activity of derivatives of phenylglyoxylic acid[J]. Pharmaceutical Chemistry Journal, 1993, 27 (3) : 195-197.|[3]Jiang W, et al., Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties. Bioorg Chem. 2020 Jan;94:103402.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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