HQ-415
HQ-415 is a biologically active metal chelator related to Clioquinol (HY-14603), with an EC50 of 15 μM.
Product Specifications
CAS Number
[430462-93-4]
UNSPSC
12352005
Target
Radionuclide-Drug Conjugates (RDCs)
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/HQ-415.html
Purity
98.05
Solubility
DMSO : 5.6 mg/mL (ultrasonic; warming)
Smiles
OC1=C2N=CC=CC2=CC=C1C(C3=CC=C(OC)C(OCC)=C3)NC4=NC=CC(C)=C4
Molecular Formula
C25H25N3O3
Molecular Weight
415.48
References & Citations
[1]Tardiff DF, et al. Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms. J Biol Chem. 2012 Feb 3;287 (6) :4107-4120.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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