Acotiamide-d6 (hydrochloride)

Acotiamide-d6 (hydrochloride) is deuterium labeled Acotiamide (hydrochloride) .

Product Specifications

Product Name Alternative

Z-338-d6 (hydrochloride) ; YM443-d6 (hydrochloride)

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

O=C(C1=CSC(NC(C2=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C2O)=O)=N1)NCCN(C(C)C)C(C)C.Cl

Molecular Formula

C21H25D6ClN4O5S

Molecular Weight

493.05

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Attia KAM, et al. Spectrofluorimetric determination of acotiamide hydrochloride trihydrate in the presence of its oxidative degradation product. Luminescence. 2018 Jun;33 (4) :806-811.|[3]Nowlan ML, et al. Acotiamide: first global approval. Drugs. 2013 Aug;73 (12) :1377-83.