Di-O-methyldemethoxycurcumin

Di-O-methyldemethoxycurcumin, a curcuminoid analog, inhibits IL-6 production with an EC50 of 16.20 μg/mL. Anti-inflammatory and antioxidant properties[1].

Product Specifications

CAS Number

[824951-60-2]

UNSPSC

12352005

Target

Interleukin Related

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/di-o-methyldemethoxycurcumin.html

Purity

97.64

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(CC(/C=C/C1=CC=C(OC)C=C1)=O)/C=C/C2=CC=C(OC)C(OC)=C2

Molecular Formula

C22H22O5

Molecular Weight

366.41

References & Citations

[1]Nuntana Aroonrerk, et al. Inhibitory effects of di-O-demethylcurcumin on interleukin-1β-induced interleukin-6 production from human gingival fibroblasts. J Dent Sci. 2012 Dec;7 (14) : 350-358.