TNIK-IN-6
TNIK-IN-6 (Compound 9) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK) and , with IC50 of 0.93 μM, that plays important roles in neurological and psychiatric disorders[1][2].
Product Specifications
CAS Number
2375196-40-8
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tnik-in-6.html
Purity
96.92
Solubility
10 mM in DMSO
Smiles
FC1=NC=CC(C2=NC3=C(N)N=CC(Br)=C3C=C2)=C1
Molecular Formula
C13H8BrFN4
Molecular Weight
319.13
References & Citations
[1]Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23 (2) :569-73.|[2]Jon Read, et al. Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase. Bioorg Med Chem Lett. 2019 Aug 1;29 (15) :1962-1967.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC401127 20 µg
TM7SF1 (GPR137B) (NM_003272) Human Over-expression Lysate
Sign In for Pricing
View Details 