KX1-004
KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL) [1][2].
Product Specifications
CAS Number
518058-84-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/KX1-004.html
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(N1)=CC2=C1C=CC(F)=C2)NCC3=CC=CC(O)=C3
Molecular Formula
C16H13FN2O2
Molecular Weight
284.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Harris KC, et al. Prevention of noise-induced hearing loss with Src-PTK inhibitors. Hear Res. 2005 Oct;208 (1-2) :14-25.|[2]Bielefeld EC, et al. A comparison of the protective effects of systemic administration of a pro-glutathione drug and a Src-PTK inhibitor against noise-induced hearing loss. Noise Health. 2005 Oct-Dec;7 (29) :24-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR214031L4V 200 µL
Olfr532 (NM_147026) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details ![N-[1-Acetyl-3- (methylsulfanyl) -1H-1,2,4-triazol-5-yl]acetamide](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
LMA31745-01 0.5 g
N-[1-Acetyl-3- (methylsulfanyl) -1H-1,2,4-triazol-5-yl]acetamide
Sign In for Pricing
View Details LMA31745-02 5 g
N-[1-Acetyl-3- (methylsulfanyl) -1H-1,2,4-triazol-5-yl]acetamide
Sign In for Pricing
View Details 
35282091 4x 500 ng
OR51B3P-set siRNA/shRNA/RNAi Lentivector (Human)
Sign In for Pricing
View Details RPU44036-01 50 µg
Recombinant Mouse Tissue Factor Pathway Inhibitor 2 (TFPI2)
Sign In for Pricing
View Details