BET-IN-25

BET-IN-25 (compound 7) is an oral bioactive inhibitor of bromodomain (BD1) and BD2, with the IC50s of 0.18 μM and 9.2 μM, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bet-in-25.html

Smiles

CN1C=C(C2=NN(C)C=C2)C(OC(CN3CCN(S(=O)(C)=O)C[C@H]3C)=C4)=C4C1=O

Molecular Formula

C19H25N5O4S

Molecular Weight

419.50

References & Citations

[1]Shuichi Hagihara, et al. Discovery of a potent, orally available furopyridine derivative as a novel selective bromodomain and extra-terminal domain (BET) -first bromodomain (BD1) inhibitor. Bioorg Med Chem Lett. 2024 Sep 1:109:129848.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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