Azacyclonol
Azacyclonol (γ-pipradol), a metabolite of Terfenadine, is a central depressant agent. Azacyclonol is a ganglion-blocking agent. Azacyclonol can be used to diminish psychoses-induced hallucinations[1][2][3].
Product Specifications
CAS Number
115-46-8
Product Name Alternative
γ-pipradol
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Azacyclonol.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C1=CC=CC=C1)(C2CCNCC2)C3=CC=CC=C3
Molecular Formula
C18H21NO
Molecular Weight
267.37
Precautions
H302, H319
References & Citations
[1]Brown DA, et, al. The effects of some centrally acting drugs on ganglionic transmission in the cat.|[2]Jurima-Romet M, et, al. Induction of CYP3A and associated terfenadine N-dealkylation in rat hepatocytes cocultured with 3T3 cells. Cell Biol Toxicol. 1995 Dec;11 (6) :313-27.|[3]BRAUN DL, et, al. The pharmacologic activity of alpha- (4-piperidyl) -benzhydrol hydrochloride (azacyclonol hydrochloride) ; an ataractive agent. J Pharmacol Exp Ther. 1956 Oct;118 (2) :153-61.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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