Azacyclonol

Azacyclonol (γ-pipradol), a metabolite of Terfenadine, is a central depressant agent. Azacyclonol is a ganglion-blocking agent. Azacyclonol can be used to diminish psychoses-induced hallucinations[1][2][3].

Product Specifications

CAS Number

[115-46-8]

Product Name Alternative

γ-pipradol

UNSPSC

12352005

Hazard Statement

H302, H319

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Azacyclonol.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C1=CC=CC=C1)(C2CCNCC2)C3=CC=CC=C3

Molecular Formula

C18H21NO

Molecular Weight

267.37

Precautions

H302, H319

References & Citations

[1]Brown DA, et, al. The effects of some centrally acting drugs on ganglionic transmission in the cat.|[2]Jurima-Romet M, et, al. Induction of CYP3A and associated terfenadine N-dealkylation in rat hepatocytes cocultured with 3T3 cells. Cell Biol Toxicol. 1995 Dec;11 (6) :313-27.|[3]BRAUN DL, et, al. The pharmacologic activity of alpha- (4-piperidyl) -benzhydrol hydrochloride (azacyclonol hydrochloride) ; an ataractive agent. J Pharmacol Exp Ther. 1956 Oct;118 (2) :153-61.