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DENV ligand 2

Product Specifications

UNSPSC Description

DENV ligand 2 is the ligand for DENV E protein.DENV ligand 2 can be utilized for synthesis of PROTAC Degrader ZXH-8-004 (HY-161806). DENV ligand 2 is the active form of DENV ligand 1 (HY-161807)[1].

Target Antigen

Dengue virus; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Anti-infection;PROTAC

Applications

Cancer-programmed cell death

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/denv-ligand-2.html

Smiles

FC(F)(F)OC1=CC=C(NC2=CC=NC(NC3=CC=C(C(O)=O)C=C3OC(F)(F)F)=N2)C=C1

Molecular Weight

474.31

References & Citations

[1]Liu HY, et al. Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism. Nat Commun. 2024 Jun 19;15(1):5179.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-161808/DENV-ligand-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-161808/

Clinical Information

No Development Reported

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