DENV ligand 2
DENV ligand 2 is the ligand for DENV E protein.DENV ligand 2 can be utilized for synthesis of PROTAC Degrader ZXH-8-004 (HY-161806) . DENV ligand 2 is the active form of DENV ligand 1 (HY-161807) [1].
Product Specifications
UNSPSC
12352005
Target
Dengue Virus; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Anti-infection; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/denv-ligand-2.html
Smiles
FC(F)(F)OC1=CC=C(NC2=CC=NC(NC3=CC=C(C(O)=O)C=C3OC(F)(F)F)=N2)C=C1
Molecular Formula
C19H12F6N4O4
Molecular Weight
474.31
References & Citations
[1]Liu HY, et al. Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism. Nat Commun. 2024 Jun 19;15 (1) :5179.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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