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Lysipressin

Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity[1][2][3][4][5].

Product Specifications

CAS Number

50-57-7

Product Name Alternative

Lysine vasopressin; [Lys8]-Vasopressin

UNSPSC

12352209

Hazard Statement

H302, H312, H332

Target

Adenylate Cyclase; Oxytocin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Lysipressin.html

Purity

99.22

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](N)CSSC1)=O)=O)([H])CC3=CC=CC=C3)=O)CCC(N)=O)=O)CC(N)=O)=O)N4[C@@H](CCC4)C(N[C@@H](CCCCN)C(NCC(N)=O)=O)=O

Molecular Formula

C46H65N13O12S2

Molecular Weight

1056.22

Precautions

H302, H312, H332

References & Citations

[1]Gorbulev V et al. Molecular cloning and functional characterization of V2 [8-lysine] vasopressin and oxytocin receptors from a pig kidney cell line. Eur J Biochem. 1993 Jul 1;215 (1) :1-7.|[2]Crankshaw D et al. [Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle.Eur J Pharmacol. 1989 Dec 7;173 (2-3) :183-8.|[3]Yu H, et al. Lysine vasopressin-induced increases in porcine myometrial contractility and intracellular Ca2+ concentrations of myometrial cells: involvement of oxytocin receptors. Biol Reprod. 1995 Mar;52 (3) :584-590.|[4]Kordower JH, et al. Central antinociceptive effects of lysine-vasopressin and an analogue. Peptides. 1982 Jul-Aug;3 (4) :613-7.|[5]Tran LD, et al. Effects of lysine-vasopressin and oxytocin on central cardiovascular control. Br J Pharmacol. 1982 Sep;77 (1) :69-73.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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