2'-Deoxycytidine
2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu) . 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2].
Product Specifications
CAS Number
951-77-9
Product Name Alternative
Deoxycytidine; Cytosine deoxyriboside; Deoxyribose cytidine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2_acute_-Deoxycytidine.html
Purity
99.95
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C1N([C@H]2C[C@H](O)[C@@H](CO)O2)C=CC(N)=N1
Molecular Formula
C9H13N3O4
Molecular Weight
227.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2 (5) :469-81.|[2]Iwazaki A, et al. Intravenously administered 2'-deoxycytidine suppresses mouse myeloma tumor growth. Biol Pharm Bull. 2012;35 (2) :251-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Citation 01
Anal Chem. 2025 May 13;97 (18) :9827-9835.|Clin Epigenetics. 2020 Feb 11;12 (1) :25.|Food Biosci. 2025 Jun.|Int J Biol Macromol. 2023 Jul 1;242 (Pt 4) :125063.|J Pharm Biomed Anal. 2025 Jun 17:265:117026.|Nature. 2025 Jul;643 (8070) :192-200.|Research Square Preprint. 2021 May.|Cell Rep. 2020 May 12;31 (6) :107640.|JCI Insight. 2022 Nov 22;7 (22) :e159419.
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