OX2R agonist 1

OX2R agonist 1 is an OX2R antagonist with an EC50 of less than 100 nM. OX2R agonist 1 can be used in research related to excessive daytime sleepiness or narcolepsy[1].

Product Specifications

CAS Number

[2648347-78-6]

UNSPSC

12352005

Target

Orexin Receptor (OX Receptor)

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ox2r-agonist-1.html

Smiles

CS(=O)(N[C@H]1CCCN2[C@H]1CO[C@H]3CC[C@H](CC3)C4=CC(F)=CC(F)=C4OCC2=O)=O

Molecular Formula

C21H28F2N2O5S

Molecular Weight

458.52

References & Citations

[1]Pennington et al, Preparation of substituted macrocyclic derivatives for use in the treatment of narcolepsy or cataplexy, US, US20210155636, 2021-05-27