Pantothenate kinase-IN-2
Product Specifications
UNSPSC Description
Pantothenate kinase-IN-2 is a potent Pantothenate kinase 1/3 (PanK1/3) inhibitor with an IC50 of 0.14 μM and 0.36 μM. Pantothenate kinase-IN-2 is a promising agent for PKAN (PanK-associated neurodegeneration) and diabetes research[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pantothenate-kinase-in-2.html
Purity
98.0
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=CC(SC)=C1)CCC2=C(C)N3C(N=C2C)=C(C=CC=N4)C4=N3
Molecular Weight
391.49
References & Citations
[1]Lalit Kumar Sharma, et al. A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases. J Med Chem. 2015 Feb 12;58(3):1563-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-44170/Pantothenate-kinase-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-44170/Pantothenate-kinase-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
902614-04-4
Available Sizes
Curated Selection
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