(R) -Camptothecin
(R) -Camptothecin is an enantiomer of Camptothecin (CPT), is inactive as an inhibitor of the DNA religation reaction and consequently do not poison Top1[1].
Product Specifications
CAS Number
110351-92-3
Product Name Alternative
(R) -Campathecin; (R) - (+) -Camptothecin; (R) -CPT
UNSPSC
12352005
Target
Drug Isomer; Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-camptothecin.html
Smiles
CC[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC=CC=C5C=C4C3)=C2)=O)O
Molecular Formula
C20H16N2O4
Molecular Weight
348.35
References & Citations
[1]Xiangshu Xiao, et al. Effect of E-Ring Modifications in Camptothecin on Topoisomerase I Inhibition: A Quantum Mechanics Treatment. J Org Chem. 2005 Nov 11;70 (23) :9584-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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