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Broflanilide

Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM[1].

Product Specifications

CAS Number

[1207727-04-5]

UNSPSC

12352005

Hazard Statement

H301, H312, H330, H410

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Broflanilide.html

Purity

98.95

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

FC(F)(F)C(F)(C1=CC(C(F)(F)F)=C(NC(C2=C(C(N(C)C(C3=CC=CC=C3)=O)=CC=C2)F)=O)C(Br)=C1)C(F)(F)F

Molecular Formula

C25H14BrF11N2O2

Molecular Weight

663.28

Precautions

H301, H312, H330, H410

References & Citations

[1]Nakao T, et al. Broflanilide: A meta-diamide insecticide with a novel mode of action. Bioorg Med Chem. 2016 Feb 1;24 (3) :372-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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