Endoglycoceramidase II (EGCase II)

Endoglycoceramidase II (EGCase II) is an endo-β-glucosidase releasing the complete glycan from ceramide in glycosphingolipids. Endoglycoceramidase II Catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides in various glycosphingolipids[1][2].

Product Specifications

CAS Number

[2763216-34-6]

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/endoglycoceramidase-ii-egcase-ii.html

Solubility

10 mM in DMSO

Smiles

[EndoglycoceramidaseII(EGCaseII)]

References & Citations

[1]Ben Bdira F, et al. Hydrophobic Interactions Contribute to Conformational Stabilization of Endoglycoceramidase II by Mechanism-Based Probes. Biochemistry. 2016 Aug 30;55 (34) :4823-35.|[2]Horibata Y, et al. Transglycosylation and reverse hydrolysis reactions of endoglycoceramidase from the jellyfish, Cyanea nozakii. J Biochem. 2001 Aug;130 (2) :263-8.