Thonningianin A

Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities[1][2].

Product Specifications

CAS Number

[271579-11-4]

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/thonningianin-a.html

Purity

99.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC(C(OC[C@@H]2[C@@H]3[C@H](OC(C4=CC(O)=C(O)C(O)=C4)=O)[C@@H](O)[C@H](OC5=CC(O)=C(C(CCC6=CC=CC=C6)=O)C(O)=C5)O2)=O)=C(C7=C(C(O3)=O)C=C(O)C(O)=C7O)C(O)=C1O

Molecular Formula

C42H34O21

Molecular Weight

874.71

References & Citations

[1]Gyamfi MA, et al. Antioxidant properties of Thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea. Biochem Pharmacol. 2002 May 1;63 (9) :1725-37.|[2]Zhang TT, et al. Effects of thonningianin A in natural foods on apoptosis and cell cycle arrest of HepG-2 human hepatocellular carcinoma cells. Food Funct. 2015 Aug;6 (8) :2588-97.