Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Llama IgG2b Fc Tag, low Endotoxin (MALS verified)
Cynomolgus / Rhesus macaque BCMA, Llama IgG2b Fc Tag (BCA-C5257) is expressed from human 293 cells (HEK293) . It contains AA Met 1 - Ala 53 (Accession # A0A2K5UD97-1) . In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus.
Product Specifications
Background
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Specifications
This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 33.8 kDa. The protein migrates as 40-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
A0A2K5UD97-1
Expression Region
Met 1 - Ala 53
Host
HEK293
Target
BCMA
Conjugation
Unconjugated
Tag
C-LlamaFc (LlamaIgG2b)
Source
Cynomolgus / Rhesus macaque
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.01 EU per μg
Purity
95%
Bioactivity
Immobilized Cynomolgus / Rhesus macaque BCMA, Llama IgG2b Fc Tag (Cat. No. BCA-C5257) at 5 μg/mL (100 μL/well) can bind Biotinylated Human BAFF, Avitag,Fc Tag (active trimer) (MALS verified) (Cat. No. BAF-H82F3) with a linear range of 0.1-8 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
33.8 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Product Datasheet
https://console.acrobiosystems.com/public/product/pdf/ds/BCA-C5257.pdf
Host or Source
HEK293
Species
Cynomolgus / Rhesus macaque
Protein ID
A0A2K5UD97-1
Preservative
Trehalose
Curated Selection
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