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CENP-E-IN-3

CENP-E-IN-3 (compound 4) is a potent CENP-E inhibitor. CENP-E-IN-3 has the potential for the research of cancer[1].

Product Specifications

UNSPSC

12352005

Target

Kinesin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cenp-e-in-3.html

Smiles

ClC1=C(OC(C)C)C=CC(C(N[C@H](C(NC)=O)CC2=CC=C(/N=N/C3=C(C)N(C(N)=O)N=C3C)C=C2)=O)=C1

Molecular Formula

C26H30ClN7O4

Molecular Weight

540.01

References & Citations

[1]Matsuo K, et al. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorg Med Chem Lett. 2024 Jul 17;111:129892.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Kinesin-7/CENP-E

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