CENP-E-IN-3
CENP-E-IN-3 (compound 4) is a potent CENP-E inhibitor. CENP-E-IN-3 has the potential for the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Kinesin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cenp-e-in-3.html
Smiles
ClC1=C(OC(C)C)C=CC(C(N[C@H](C(NC)=O)CC2=CC=C(/N=N/C3=C(C)N(C(N)=O)N=C3C)C=C2)=O)=C1
Molecular Formula
C26H30ClN7O4
Molecular Weight
540.01
References & Citations
[1]Matsuo K, et al. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorg Med Chem Lett. 2024 Jul 17;111:129892.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Kinesin-7/CENP-E
Curated Selection
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