Tenalisib R Enantiomer
Tenalisib R Enantiomer (RP6530 R Enantiomer) is an R enantiomer of Tenalisib. Tenalisib is a potent and selective PI3Kδ and PI3Kγ inhibitor with IC50 values of 25 and 33 nM, respectively[1][2].
Product Specifications
CAS Number
[1639417-54-1]
Product Name Alternative
RP6530 R Enantiomer
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Tenalisib_R_Enantiomer.html
Concentration
10mM
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C2=CC=CC(F)=C2)=C([C@H](NC3=C4N=CNC4=NC=N3)CC)OC5=CC=CC=C15
Molecular Formula
C23H18FN5O2
Molecular Weight
415.42
References & Citations
[1]Swaroop Vakkalanka, et al. Abstract 2704: RP6530, a dual PI3K δ/γ inhibitor, potentiates ruxolitinib activity in the JAK2-V617F mutant erythroleukemia cell lines.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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