αvβ6-IN-2
αvβ6-IN-2 (compound 20) is a potent and orally active αvβ6 integrin inhibitor with a pIC50 value of 7.8. αvβ6-IN-2 has the potential for the research of idiopathic pulmonary fibrosis[1].
Product Specifications
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/αvβ6-in-2.html
Smiles
COC1=CC(C(CC(O)=O)CN2CC(C(F)(CCC3=NC4=C(CCCN4)C=C3)F)C2)=CC=C1F
Molecular Formula
C25H30F3N3O3
Molecular Weight
477.52
References & Citations
[1]Hryczanek HF, et al. Core Modifications of GSK3335103 toward Orally Bioavailable αvβ6 Inhibitors with Improved Synthetic Tractability. J Med Chem. 2024 Oct 17
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
αvβ6
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
057551-01 10 µg
G Protein Alpha Activating Activity Polypeptide O (GNaO1), Recombinant, Human, His-Tag
Sign In for Pricing
View Details 057551-02 50 µg
G Protein Alpha Activating Activity Polypeptide O (GNaO1), Recombinant, Human, His-Tag
Sign In for Pricing
View Details 057551-03 100 µg
G Protein Alpha Activating Activity Polypeptide O (GNaO1), Recombinant, Human, His-Tag
Sign In for Pricing
View Details 057551-04 200 µg
G Protein Alpha Activating Activity Polypeptide O (GNaO1), Recombinant, Human, His-Tag
Sign In for Pricing
View Details 