(R)-IHMT-PI3Kδ-372

Product Specifications

UNSPSC Description

(R)-IHMT-PI3Kδ-372 (R-18) is a potent and selective PI3Kδ inhibitor with an IC50 of 19 nM. (R)-IHMT-PI3Kδ-372 (R-18) can be used in chronic obstructive pulmonary disease (COPD) research[1].

Target Antigen

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/r-ihmt-pi3kδ-372.html

Purity

99.75

Smiles

CC[C@H](C(N1C2CC2)=NC3=CC=CC(F)=C3C1=O)N4C5=NC=NC(N)=C5C(C6=CC(F)=C(C=C6)OC)=N4

Molecular Weight

503.50

References & Citations

[1]Li F, et al. Discovery of (S)-2-(1-(4-Amino-3-(3-fluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)propyl)-3-cyclopropyl-5-fluoroquinazolin-4(3H)-one (IHMT-PI3Kδ-372) as a Potent and Selective PI3Kδ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease. J Med Chem. 2020 Nov 25;63(22):13973-13993.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-131910A/R-IHMT-PI3Kδ-372-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-131910A/R-IHMT-PI3Kδ-372-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2429889-62-1

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-97207JF549 0.1 mL

Rabbit Polyclonal GBP6 Antibody [Janelia Fluor 549]

Ask

View Details

NB100-60669IR 0.1 mL

Rabbit Polyclonal DOCK10 Antibody [DyLight 755]

Ask