HSD17B13-IN-4
HSD17B13-IN-4 (Compound 95) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with a Ki value of ≤ 50 nM for the estradiol substrate LCMS. HSD17B13-IN-4 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI) [1].
Product Specifications
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-4.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC(C2=NC(C(NCC3=CC=CC=C3C(F)(F)F)=O)=C(S2)NC(C4=CC(Cl)=C(C(Cl)=C4)O)=O)=CC=C1
Molecular Formula
C26H15Cl2F3N4O3S
Molecular Weight
591.39
References & Citations
[1]Joshua Odingo, et al. 2-substituted thiazole hsd17b13 inhibitors and uses thereof. WIPO, WO2023146897. 2023-08-03.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![5-Nitro[1,1'-biphenyl]-2,2'-diamine](https://cdn.genprice.uk/products/572/2082784343922/imageurl/trc-n494020-250mg.webp)
