NMS-P953
Product Specifications
UNSPSC Description
NMS-P953 (compound 28) is an orally active JAK2 inhibitor (IC50=0.008 μM) with antitumor activity[1].
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nms-p953.html
Smiles
O=C(C1=C(C2=CC(C(F)(F)F)=CC=C2Cl)NC(C3=NC(N)=NC=C3)=C1)N
Molecular Weight
381.74
References & Citations
[1]Brasca M G, et al. Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors[J]. Bioorganic & Medicinal Chemistry, 2014, 22(17): 4998-5012.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129679/NMS-P953-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129679/
Clinical Information
No Development Reported
CAS Number
1403679-33-3
Curated Selection
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