Virstatin

Virstatin inhibits the pili system synthesis and prevents A. baumannii biofilm formation. Virstatin also inhibits dimerization of the transcriptional activator ToxT[1][2].

Product Specifications

CAS Number

[88909-96-0]

UNSPSC

12352005

Hazard Statement

H302, H318, H410

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/virstatin.html

Purity

98.00

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N(C1=O)CCCC(O)=O)C2=CC=CC3=CC=CC1=C23

Molecular Formula

C16H13NO4

Molecular Weight

283.28

Precautions

H302, H318, H410

References & Citations

[1]Nait Chabane Y, et al. Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii. BMC Microbiol. 2014 Mar 12;14:62.|[2]Shakhnovich EA, et al. Virstatin inhibits dimerization of the transcriptional activator ToxT. Proc Natl Acad Sci U S A. 2007 Feb 13;104 (7) :2372-7.