Virstatin
Virstatin inhibits the pili system synthesis and prevents A. baumannii biofilm formation. Virstatin also inhibits dimerization of the transcriptional activator ToxT[1][2].
Product Specifications
CAS Number
[88909-96-0]
UNSPSC
12352005
Hazard Statement
H302, H318, H410
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/virstatin.html
Purity
98.00
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N(C1=O)CCCC(O)=O)C2=CC=CC3=CC=CC1=C23
Molecular Formula
C16H13NO4
Molecular Weight
283.28
Precautions
H302, H318, H410
References & Citations
[1]Nait Chabane Y, et al. Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii. BMC Microbiol. 2014 Mar 12;14:62.|[2]Shakhnovich EA, et al. Virstatin inhibits dimerization of the transcriptional activator ToxT. Proc Natl Acad Sci U S A. 2007 Feb 13;104 (7) :2372-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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