SIA Crosslinker
SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
39028-27-8
Product Name Alternative
Iodoacetic acid N-hydroxysuccinimide ester; N-Succinimidyl Iodoacetate
UNSPSC
12352203
Hazard Statement
H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sia-crosslinker.html
Purity
98.0
Solubility
DMF : ≥ 100 mg/mL|DMSO : ≥ 100 mg/mL
Smiles
O=C(ON1C(CCC1=O)=O)CI
Molecular Formula
C6H6INO4
Molecular Weight
283.02
Precautions
H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Grm5 (824-1203, Cytopl. Dom.) Mouse Monoclonal Antibody [Clone ID: N75/3]](https://cdn.genprice.uk/products/937/68dd1898061270361e8fb3d4/imageurl/75-115.webp)
75-115 100 µL
Grm5 (824-1203, Cytopl. Dom.) Mouse Monoclonal Antibody [Clone ID: N75/3]
Sign In for Pricing
View Details ![Synaptophysin (SYP) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A1]](https://cdn.genprice.uk/products/937/6868c368994c49e6dc3f6c84/imageurl/ta506105am.webp)
TA506105AM 100 µL
Synaptophysin (SYP) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A1]
Sign In for Pricing
View Details 
BNC040413-500 1x 500 µL
Chromogranin A (CHGA/413), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB3089-500 1x 500 µL
MSH6 (DNA Mismatch Repair Protein) (MSH6/3089), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 