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cIAP1 Ligand-Linker Conjugates 4

Product Specifications

Product Name Alternative

E3 ligase Ligand-Linker Conjugates 42

UNSPSC Description

cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs[1].

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-42.html

Solubility

10 mM in DMSO

Smiles

C[C@H](N(C(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)C)C(N[C@@H](C4CCCCC4)C(N(CCC5)[C@@H]5C(N[C@@H](C(C6=CC=CC=C6)C7=CC=CC=C7)C(NCCOCCOCCOCC(O)=O)=O)=O)=O)=O

Molecular Weight

974.15

References & Citations

[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-128821/cIAP1-Ligand-Linker-Conjugates-4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-128821/

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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