CIAP1 Ligand-Linker Conjugates 4

CIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs[1].

Product Specifications

Product Name Alternative

E3 ligase Ligand-Linker Conjugates 42

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-42.html

Solubility

10 mM in DMSO

Smiles

C[C@H](N(C(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)C)C(N[C@@H](C4CCCCC4)C(N(CCC5)[C@@H]5C(N[C@@H](C(C6=CC=CC=C6)C7=CC=CC=C7)C(NCCOCCOCCOCC(O)=O)=O)=O)=O)=O

Molecular Formula

C55H67N5O11

Molecular Weight

974.15

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19 (22) :6768-78.