Notopterol

Notopterol is a coumarin extracted from N. incisum. Notopterol induces apoptosis and has antipyretic, analgesic and anti-inflammatory effects. Notopterol is used for acute myeloid leukemia (AML) [1].

Product Specifications

CAS Number

[88206-46-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/notopterol.html

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=CC2=C(OC/C=C(C)/CC(O)/C=C(C)/C)C3=C(OC=C3)C=C2O1

Molecular Formula

C21H22O5

Molecular Weight

354.40

Precautions

H302, H315, H319, H335

References & Citations

[1]Huang Q, et al. Notopterol-induced apoptosis and differentiation in human acute myeloid leukemia HL-60 cells. Drug Des Devel Ther. 2019 Jun 6;13:1927-1940.