Cyclo (Gly-Arg-Gly-Asp-Ser-Pro)
Cyclo (Gly-Arg-Gly-Asp-Ser-Pro) (c (GRGDSP) ) is an RGD-containing inhibitory peptide. Cyclo (Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells[1].
Product Specifications
CAS Number
[135432-37-0]
Product Name Alternative
C (GRGDSP)
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclo-gly-arg-gly-asp-ser-pro.html
Purity
98.11
Solubility
H2O : ≥ 100 mg/mL
Smiles
O=C1N2[C@@](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H]1CO)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)=O)([H])CCC2
Molecular Formula
C22H35N9O9
Molecular Weight
569.57
References & Citations
[1]Kumagai H, et al. Effect of cyclic RGD peptide on cell adhesion and tumor metastasis. Biochem Biophys Res Commun. 1991 May 31;177 (1) :74-82.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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