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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)

Product Specifications

UNSPSC Description

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells[1].

Target Antigen

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cyclo-gly-arg-gly-asp-ser-pro.html

Purity

98.11

Solubility

10 mM in DMSO

Smiles

O=C1N2[C@@](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H]1CO)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)=O)([H])CCC2

Molecular Weight

569.57

References & Citations

[1]Kumagai H, et al. Effect of cyclic RGD peptide on cell adhesion and tumor metastasis. Biochem Biophys Res Commun. 1991 May 31;177(1):74-82.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P5038/Cyclo-Gly-Arg-Gly-Asp-Ser-Pro-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P5038/Cyclo-Gly-Arg-Gly-Asp-Ser-Pro-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

135432-37-0

Available Sizes

Curated Selection

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