BRD-K56819078

BRD-K56819078 is a Bcl-2 inhibitor that significantly reduces senescent cell load and senescence-related genes in the kidney mRNA expression. BRD-K56819078 exerts anti-aging effects by inhibiting apoptosis[1].

Product Specifications

CAS Number

[693231-07-1]

UNSPSC

12352005

Target

Apoptosis; Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/brd-k56819078.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=C(C=C(C=C1)C(NC2=CC3=C(N=C(S3)SCC(NC4=CC=CC=C4F)=O)C=C2)=O)OC

Molecular Formula

C24H20FN3O4S2

Molecular Weight

497.56

References & Citations

[1]Wong F, et al. Discovering small-molecule senolytics with deep neural networks. Nat Aging. 2023 Jun;3 (6) :734-750.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS350006-01 1 mL

Anti-human Epidermal Growth Factor Monoclonal Antibody Clone 1B11-3E12

Ask

View Details

MBS350006-02 5x 1 mL

Anti-human Epidermal Growth Factor Monoclonal Antibody Clone 1B11-3E12

Ask

View Details

NBP2-98079FR 0.1 mL

Rabbit Polyclonal TNRC6B Antibody [DyLight 680]

Ask

View Details

MBS2605774-01 48 Well

Canine Tripartite motif-containing protein 3 (TRIM3) ELISA Kit

Ask

View Details

MBS2605774-02 96 Well

Canine Tripartite motif-containing protein 3 (TRIM3) ELISA Kit

Ask

View Details

MBS2605774-03 5x 96 Well

Canine Tripartite motif-containing protein 3 (TRIM3) ELISA Kit

Ask

View Details