BRD-K56819078
BRD-K56819078 is a Bcl-2 inhibitor that significantly reduces senescent cell load and senescence-related genes in the kidney mRNA expression. BRD-K56819078 exerts anti-aging effects by inhibiting apoptosis[1].
Product Specifications
CAS Number
[693231-07-1]
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/brd-k56819078.html
Concentration
10mM
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(C=C(C=C1)C(NC2=CC3=C(N=C(S3)SCC(NC4=CC=CC=C4F)=O)C=C2)=O)OC
Molecular Formula
C24H20FN3O4S2
Molecular Weight
497.56
References & Citations
[1]Wong F, et al. Discovering small-molecule senolytics with deep neural networks. Nat Aging. 2023 Jun;3 (6) :734-750.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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