Beaucage reagent
Selected Variant
HY-100951-01
Size: 250 mg
Beaucage reagent is found to be potent in causing DNA cleavage[1][2][3].
Product Specifications
CAS Number
66304-01-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Beaucage-reagent.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL|H2O : 0.14 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=C12)SS2(=O)=O
Molecular Formula
C7H4O3S2
Molecular Weight
200.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Zheng J, et al. Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent. Org Biomol Chem. 2010 Mar 21;8 (6) :1293-5.|[2]C. F. H. Allen, et al. Working with Hazardous Chemicals. Organic Syntheses, Coll. Vol. 2, 1943, 580.|[3] Stec W J, et al. Bis (O, O-diisopropoxy phosphinothioyl) disulfide-a highly efficient sulfurizing reagent for cost-effective synthesis of oligo (nucleoside phosphorothioate) s[J]. Tetrahedron letters, 1993, 34 (33) : 5317-5320.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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Price
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