hCAIX-IN-18
Product Specifications
UNSPSC Description
hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-in-18.html
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)
Smiles
ClC1=CC=C(/C(N2CCN(C3=CC=C(S(=O)(N)=O)C=C3)CC2)=N\O)C=C1
Molecular Weight
394.88
References & Citations
[1]1. Peerzada MN, et al. Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors. ACS Med Chem Lett. 2023 May 8;14(6):810-819.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149301/hCAIX-IN-18-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149301/hCAIX-IN-18-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2925261-76-1
Available Sizes
Curated Selection
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