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hCAIX-IN-18

Product Specifications

UNSPSC Description

hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].

Target Antigen

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hcaix-in-18.html

Solubility

DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)

Smiles

ClC1=CC=C(/C(N2CCN(C3=CC=C(S(=O)(N)=O)C=C3)CC2)=N\O)C=C1

Molecular Weight

394.88

References & Citations

[1]1. Peerzada MN, et al. Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors. ACS Med Chem Lett. 2023 May 8;14(6):810-819.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-149301/hCAIX-IN-18-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-149301/hCAIX-IN-18-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2925261-76-1

Available Sizes

Curated Selection

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